Small mammals – natural reservoir of pathogenic leptospires

نویسندگان

  • F. TREML
  • M. PEJČOCH
  • Z. HOLEŠOVSKÁ
چکیده

A total of 429 specimens belonging to 9 species of small mammals, trapped in various areas of the Czech Republic during the year 2001, were examined for antibodies against leptospires. Antibodies were found in all localities under study in 50 specimens, i.e., 11.6%, belonging to 5 species. Antibodies were most often , i.e., in 42% of positives, found in Microtus arvalis. In Apodemus spp. and Clethrionomys glareolus it was in 34.0% and 14.0% of positives, respectively. In other specimens belonging to Mus musculus and Microtus subterraneus antibodies were found only on occasion. Antibodies against L. grippotyphosa serotype were only found. Titres varied from 100 to 12 800 and most reactions in positive individuals were at lower dilutions, i.e., up to the titre of 800 in 40 cases (80%). e results proved the already known fact of dominant persistence of leptospiral foci of the grippotyphosa type in the Czech Republic.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparative Proteomic Analysis of Differentially Expressed Proteins in the Urine of Reservoir Hosts of Leptospirosis

Rattus norvegicus is a natural reservoir host for pathogenic species of Leptospira. Experimentally infected rats remain clinically normal, yet persistently excrete large numbers of leptospires from colonized renal tubules via urine, despite a specific host immune response. Whilst persistent renal colonization and shedding is facilitated in part by differential antigen expression by leptospires ...

متن کامل

Natural antibody in mammalian serum reacting with an antigen in some leptospires.

Serum from normal mammals agglutinated and immobilized nonpathogenic Leptospira biflexa and agglutinated avirulent lines of pathogenic serotypes L. icterohaemorrhagiae and L. zanoni. Virulent lines of L. icterohaemorrhagiae and L. zanoni were not affected, nor were any of three strains of L. pomona, one of which was avirulent. The active principle in serum was a beta-macroglobulin which was hea...

متن کامل

Survey of leptospirosis of small mammals in Thailand.

During 1999-2000, kidney tissues of approximately 15% of 1310 rodents trapped from northeastern provinces of Thailand were tested for the presence of leptospires. Our direct immunofluorescent assay (DFA) for detection of leptospires showed 100% sensitivity and 94% specificity with the culture data. Both methods identified R. norvegicus as the highest source of infection. Among isolated Leptospi...

متن کامل

Interaction of leptospires with murine microglial cells.

Leptospires, the agents of leptospirosis, exert tropism for the central nervous system, in the course of mammal infection. We evaluated the interaction between murine microglial cells and strains of pathogenic L. interrogans leptospires and non-pathogenic L. biflexa leptospires, mainly by flow cytometric assays. In the absence of opsonic conditions microglia are capable of ingesting--even quite...

متن کامل

Agglutinating antibodies against pathogenic Leptospira in healthy dogs and horses indicate common exposure and regular occurrence of subclinical infections.

Clinical leptospirosis in dogs is often associated with ent exposure, directly, or indirectly, to surface water taminated by brown rat urine. Interestingly, Weil’s ase, the most prominent clinical presentation of tospirosis mostly occurs as an individual case, although re individuals have usually been exposed to the same sumed source. In horses, clinical leptospirosis has a low idence and the m...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2002